Focus
Our lab primarily focuses on bioinformatics, health informatics and integrative
analyses. We use high-throughput technologies to examine and model molecular
mechanisms of biological processes.
The Kolker Lab at the Seattle
Children's Research Institute uses approaches such as genome-wide gene,
protein, and metabolite expression, complemented with mutagenesis, biochemical,
and physiological experiments. Integration and analysis of these multivariate
data will be implemented through comprehensive computations, including
bioinformatics, statistics, and mathematical modeling. The deeper knowledge
of cellular behavior and responses will enable the researches at the Kolker
Lab to develop improvements to human health and address environmental
concerns.
Research
- Software and statistical methods for the analysis of proteomics data
- Web application for teens with diabetes
- Experimental standards for high-throughput
- Web Predictive analytics to improve hospital care and management
- Functional annotation of proteins
- Integrative studies of clinical samples and model systems
Our Supporters
National Institute of General Medical Services,
NIH
National Institute of Diabetes and Digestive and Kidney Diseases,
NIH
National Heart, Lung, and Blood Institute, NIH
National Science Foundation
Microsoft Research Be Well Fund
Hydrocephalus Research Guild McMillen Foundation
Foster Promise - A community
committed to all our children